Effects of Dietary Natural Mycotoxins Exposure on Performance, Biochemical Parameters and Milk Small Molecule Metabolic Pathways of Lactating Cows

The presence of mycotoxins in feed has the potential to cause significant detriment animal and human health, even severe economic implications. Previous studies on effects mainly focused addition commercially available into feeds animals. In present study, corn meal cottonseed were kept warm humid conditions allow for produced then used substitute 50% 100% normal diets lactating cows 14 days. results showed that aflatoxin M1, deoxynivalenol, B1, zearalenone primary milk from fed diets. Compared with control group, feeding containing mildewy reduced intake, yield, fat, protein lactose productions (p > 0.05). No difference was observed acetate valerate concentrations, propionate ratio, calculated CH4 production rumen fluid 0.05), whereas, propionate, butyrate, isovalerate concentrations affected < 0.05) depending content type natural mycotoxins. Serum creatinine total glyceride influenced fully replaced feeds. Metabolic pathways small molecule metabolites altered by dietary mycotoxin exposures, changes associated amino acid metabolism, glucose energy metabolism. However, exposed still healthy had low somatic cell count milk.